PLECTRANTHUS VETTIVEROIDES (VILAMICHAI) AND ITS POTENTIAL THERAPEUTIC ROLE IN MENSTRUAL DISORDERS: A COMPREHENSIVE EXPLORATION.

Abstract

Menstrual disorders, encompassing dysmenorrhea, menorrhagia, and irregular cycles, significantly impact women globally, challenging their well-being. Traditional medicine, rooted in natural remedies like Plectranthus vettiveroides (Indian Coleus), holds historical significance in addressing such concerns, particularly in Ayurveda.

1. vettiveroides, a staple in Ayurvedic formulations, reflects a cultural reliance on its efficacy for women's reproductive health over millennia. Its pharmacological richness, featuring diterpenoids, essential oils, and flavonoids, suggests potential relief from menstrual disorders. Diterpenoids show anti-inflammatory effects, essential oils may aid muscle relaxation, and flavonoids contribute antioxidant and anti-inflammatory properties.

Historically, P. vettiveroides' use in Ayurveda aligns with its enduring wisdom, dating back to 1500 BCE. Scientific studies support its therapeutic potential, with essential oils demonstrating muscle relaxant effects and flavonoids modulating inflammatory pathways.

Moreover, the root essential oil exhibits vasorelaxant properties, suggesting potential as an antihypertensive drug. Leaf powder infusion shows antipyretic activity, hinting at natural remedies for fever, with potential antidyslipidemic effects. In silico studies propose leads against type II diabetes in P. vettiveroides. Eventhough there is a confusion in nomenclature of vetti ver and vilamichai ver, we have tried to focus on the later only.

While these findings highlight the botanical's promise, comprehensive research, including clinical trials, is crucial for establishing safety and efficacy. In conclusion, P. vettiveroides' chemical profile opens avenues for exploring its therapeutic effects on menstrual health, bridging traditional wisdom with modern scientific understanding. Continued research will unveil mechanisms and validate this botanical remedy's potential, offering holistic approaches to women's well-being.